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SAN FRANCISCO (AP) — San Francisco Mayor London Breed pledged for the second time in a year Wednesday to crack down on open-air opioid drug sales and rampant public drug use that she says is destroying the city.

JACKSON, Mich. — Postings in chatrooms by members of a paramilitary group connected to a 2020 anti-government plot to kidnap Michigan Gov. Gretchen Whitmer included instructions on how to make explosives, an FBI agent testified Wednesday.

OTTAWA — The federal government has tabled a long-awaited plan in the House of Commons to improve access to diabetes treatment and prevention in Canada, Health Minister Jean-Yves Duclos announced Wednesday.

OTTAWA — Refugee and human-rights advocates are telling the Supreme Court of Canada that a binational pact "contracts out" Canada's international obligations to refugee claimants to the United States, without proper followup to ensure Washington is d

Winnipeg police announced charges against five more people Wednesday, a day after dismantling a protest camp on the north lawn of the Manitoba legislature near the main entrance to the building.

PORTLAND, Maine (AP) — A congressman from Maine said Wednesday he will file a proposal to withhold federal money from a California aquarium and conservation group that has recommended seafood consumers avoid buying lobster.

VICTORIA — British Columbia Premier John Horgan is travelling to San Francisco for meetings with leaders of U.S. West Coast states, where he expects to sign up to joint action on climate change.

COLUMBUS, Ohio (AP) — Democratic U.S. Rep. Tim Ryan, who has made his opponent's questionable record fighting the opioid epidemic a central theme of his campaign for Ohio's open U.S.

OTTAWA — The new sport integrity commissioner needs to do a wider inquiry digging into a toxic culture of abuse in Canadian sporting organizations, federal Sport Minister Pascale St-Onge said Wednesday.

OTTAWA — Justice Minister David Lametti said Canada still hasn't sorted out how to solve an issue other countries fixed months ago, leaving Canadian humanitarian groups unable to help desperate Afghans.